GAP JUNCTION-RIBOSOME ASSOCIATION AFTER AUTOLYSIS
نویسندگان
چکیده
منابع مشابه
Gap Junction-ribosome Association after Autolysis
Cell membrane integrity and regularity are criteria commonly used to appreciate the preservation of biological specimens in electron microscope preparations . Disruptions in the cell membrane are observed in tissues experimentally submitted to autolysis and are interpreted as an expression of the fragility of autolysed tissues during technical procedures. In liver cells, on which most of the st...
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Gap junctions are known to present a variety of different morphologies in electron micrographs and x-ray diffraction patterns. This variation in structure is not only seen between gap junctions in different tissues and organisms, but also within a given tissue. In an attempt to understand the physiological meaning of some aspects of this variability, gap junction structure was studied following...
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When cloned hybrid cells (A/Bm-5) were grown to confluence and fixed in glutaraldehyde-calcium, electron-opaque deposits were observed on the cytoplasmic faces of plasma membrane. Deposits were most abundant at gap junctions. Deposits were often precisely paired, cell-to-cell, across the gap junctional membranes, and these paired deposits were frequently equivalent in size. This relationship wa...
متن کاملOn gap junction structure
We have studied the stain distribution within rat liver gap junctions for specimens prepared by thin sectioning and negative staining. Pools of stain molecules exist in two specific locations with respect to the distinctive morphological units (connexons) of the junction. One pool of stain surrounds the connexons and is restricted to the extracellular space in the gap between the adjacent plasm...
متن کاملNonredundant gap junction functions.
The need for molecular heterogeneity of gap junction channel proteins in vivo has been enigmatic. Recently, functional replacement of one channel gene with another in mice and flies has revealed that cellular health depends not simply on gap junction communication but also requires the correct type of intercellular channel subunit.
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1973
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.58.1.226